2009 & 2010 Chapter Meeting Presentations: Presentations from the Annual Chapter Meetings held in October 2009 & 2010. All files are in a MS PowerPoint Show (.PPS) format. You do not need to have MS PowerPoint Installed on your computer to view the files. Each link opens a new window. View 2010 Presentations View 2009 Presentations For presentations prior to 2009, please contact PaACC. Type-2 Diabetes Mellitus: T2DM Drivers Driver One Reducing blood glucose and HbA1c levels reduces the risk of diabetic complications. Intensive therapy has been shown to be superior to conventional therapy in terms of reducing glycemia and diabetic complications. Driver Two When monotherapy with an oral agent is no longer adequate, combination therapy with two or more oral agents has been shown to significantly improve glycemic control. Driver Three When oral monotherapy or combination oral therapy is no longer adequate, insulin can be added to the regimen to significantly improve glycemic control. Driver Four Benefits of insulin therapy, such as improved outcomes and glycemic control, outweigh risks such as the potential for inducing hypoglycemia. Driver Five Type 2 diabetes mellitus is a disease consisting of two components: insulin resistance and insulin deficiency. Read the full diabetes module for cardiology. This Scientific Evidence Based Medicine Module was funded by an educational grant from Sanofi-Aventis Pharmaceuticals Education Center.